Specialized Care for Individuals Diagnosed Before Age 50

At the University of Chicago Medicine, we recognize the increasing incidence of gastrointestinal (GI) cancers, including colorectal cancer, among adults under 50. Our Early-Onset Gastrointestinal Cancer Program is designed to address the distinct medical, psychosocial and research needs of younger patients through a comprehensive and multidisciplinary approach.

Gastrointestinal cancers originate in the digestive tract, affecting organs such as the colon, rectum, stomach, pancreas, gall bladder, biliary system, anus and esophagus. At UChicago Medicine, our experts are committed to advancing early detection, delivering state-of-the-art treatment and improving outcomes for younger GI cancer patients.

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Multidisciplinary Treatment Approach

UChicago Medicine employs a personalized, evidence-based treatment model incorporating the latest advancements in GI oncology. Our approach includes:

• Minimally invasive surgical techniques to optimize recovery and reduce postoperative complications
• Tailored chemotherapy and targeted therapeutic regimens, designed to achieve optimal oncologic outcomes while minimizing treatment-related toxicities
• Innovative immunotherapy protocols, including clinical trials evaluating novel interventions with promising efficacy
• Precision imaging-guided therapies, leveraging CT and MRI technology for enhanced localization and treatment planning Each patient's treatment plan is developed collaboratively in a multidisciplinary way to ensure individualized, high-quality care.

Early-Onset Colorectal Cancer: Risk Factors and Screening Guidelines

• Individuals under 50 years of age are classified as early-onset colorectal cancer patients.
• Projections indicate that by 2030, the incidence of colon cancer will double and rectal cancer will quadruple in this demographic.
• Established risk factors include genetic predisposition, inflammatory bowel disease (IBD), obesity, tobacco use, alcohol consumption and environmental influences.
• Given these trends, guidelines now recommend colorectal cancer screening starting at age 45 to enhance early detection.

Why Choose UChicago Medicine?

UChicago Medicine offers a comprehensive, integrated program that combines expert clinical care with cutting-edge research and specialized support services. Our approach includes:

• Screening programs for colorectal cancer and pancreatic cancer
• Cancer risk assessment through the genetics program
• A multidisciplinary team comprising GI oncologists, surgeons, radiation oncologists, interventional radiologists and gastroenterologists
• Supportive services with psycho-oncology specialists, specialists for men’s and women’s reproductive and sexual health, palliative care services, acupuncture and long and short term survivorship support
• Advanced treatment modalities, including minimally invasive surgery, hepatic arterial pump, and liver-directed therapies such as:
  •  Y-90
  • Histotripsy
  • Liver transplant
  • HIPEC
  • PIPEC
  • Stereotactic body radiation therapy (SBRT)
  • Clinical trials

Psychosocial and Supportive Care Services

Recognizing the significant impact of cancer beyond its physiological manifestations, UChicago Medicine provides comprehensive psychosocial support to address the unique challenges faced by younger patients. Our Supportive Oncology Program offers:

• Oncology psychiatry and psychology for mental health support and coping strategies
• Specialized social work resources for patients and their caregivers
• Fertility preservation and counseling for individuals considering future reproductive options
• Sexual health consultation to manage treatment-related effects on sexual function
• Oncology-specific nutrition counseling tailored to the needs of GI cancer patients

Ongoing Research and Clinical Trials

If you’ve been diagnosed with early-onset gastrointestinal cancer, new treatment options are being explored through ongoing clinical trials. These studies aim to advance care, improve outcomes and provide access to cutting-edge therapies. You may be eligible to participate in a trial, which could offer new possibilities in your treatment journey. Learn more and find available clinical trials.

Support Early-Onset GI Cancer Research

Your philanthropic support helps drive innovative research and specialized care for patients facing early-onset gastrointestinal cancers at the University of Chicago Medicine. Make a gift today to help advance this vital work and improve outcomes for patients and families.

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Patients diagnosed with GI cancer before age 50 are eligible for specialized care at UChicago Medicine.