UChicago Medicine Comprehensive Cancer Center

The University of Chicago Medicine Endocrine Genetics Clinic is a collaboration between the Comprehensive Cancer Risk and Prevention Clinic and the Endocrine Surgery Clinic.

Our team includes a certified genetic counselor and endocrine surgery experts who work together to offer comprehensive risk assessment to patients with suspected inherited endocrine tumor syndromes.

Patients meet with our genetic counselor to review family medical history and discuss options for genetic testing. A board-certified endocrine surgeon provides recommendations for disease management.

Our Endocrine Genetics Clinic welcomes individuals and families with one or more of the following endocrine disorders:

  • Adrenocortical carcinoma (before age 40)
  • Familial non-medullary thyroid cancer
    • Any patient who has a relative with papillary or follicular thyroid cancer
    • Any patient under age 18 diagnosed with papillary or follicular thyroid cancer
  • Foregut carcinoids (bronchial, thymic, gastric)
  • Medullary thyroid cancer (any age)
  • Multifocal pancreatic neuroendocrine tumors
  • Multiglandular primary hyperparathyroidism (before age 40)
  • Paragangliomas (any age)
  • Parathyroid carcinoma
  • Pheochromocytomas
    • Any patient diagnosed before age 40
    • Malignant or multiple
  • Pituitary tumors (before age 25)
  • Two primary malignancies in the same individual, such as:
    • Thyroid and breast
    • Thyroid and endometrial
    • Thyroid and renal cell carcinoma (RCC)
    • RCC and breast

Examples of common syndromes seen in our Endocrine Genetics Clinic include:

  • Multiple endocrine neoplasia type 1 (MEN1): parathyroid, pituitary, pancreas tumors
  • Multiple endocrine neoplasia type 2 (MEN2): medullary thyroid cancer; parathyroid, renal tumors
  • Hereditary pheochromocytoma/paraganglioma syndrome: pheo/paraganglioma; kidney cancer, gastrointestinal stromal tumor (GIST)
  • Von Hippel-Lindau disease (VHL): kidney cancer, brain, spine, adrenal, pancreatic 
  • Others including: Cowden syndrome, neurofibromatosis type 1, jaw tumor-hyperparathyroidism syndrome, familial hyperparathyroidism, Carney complex

Endocrine Genetics Team

Endocrine Surgery
Peter Angelos, MD, PhD

Walter Stadler, MD, medical oncologist

Cancer Care Second Opinions

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Participate in a Clinical Trial

We're actively conducting clinical trials for thyroid cancer.

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Diagnosis & Treatment of Endocrine Diseases

Our team can treat a wide range of endocrine conditions, from common diseases like diabetes to rare genetic disorders.