Jeffrey B. Matthews, MD

Gastrointestinal Surgery (GI Surgery), General Surgery, Surgical Oncology | More

Dallas B. Phemister Professor of Surgery Chair, Department of Surgery

UChicago Faculty Physicians hold faculty positions with the University of Chicago and provide care for patients on the academic health system’s main campus in Hyde Park and in care centers throughout the Chicago region.


Jeffrey B. Matthews, MD, is a gastrointestinal surgeon and leading authority on the surgical treatment of diseases of the pancreas and bile ducts. He is highly skilled in the treatment of acute and chronic pancreatitis, and is one of a handful of surgeons in the nation who has expertise in islet autotransplantation, a treatment for severe pancreatitis with and without a genetic component. He also has vast experience in bile duct reconstruction and complex reoperative gastrointestinal surgery.

Dr. Matthews has held several leadership positions during his distinguished career. Currently, he is the chair of the Surgery Residency Review Committee of the Accreditation Council for Graduate Medical Education. He is a senior director of the American Board of Surgery and past-president of the Society of Surgical Chairs, the Society of University Surgeons and the Society for Surgery of the Alimentary Tract (SSAT). Dr. Matthews led a federally funded research laboratory for over two decades studying the regulation of epithelial transport and barrier function. His research received long-term support from the National Institutes of Health.

An accomplished author, Dr. Matthews has published over 200 original articles, chapters and editorials, as well as multiple surgical textbooks. He serves on the editorial board of 11 prestigious surgical and scientific journals and is Editor-in-Chief Emeritus of the Journal of Gastrointestinal Surgery.

Dr. Matthews is dedicated to teaching and mentoring medical students and new physicians, and has received awards for excellence in teaching. A popular speaker, Dr. Matthews is frequently invited to lecture at universities and medical conferences across the United States and abroad.

Areas of Expertise

Medical Education

  • Harvard University Medical School


  • Beth Israel Deaconess Medical Center


  • Beth Israel Deaconess Medical Center


  • University Hospital of Bern

Memberships & Medical Societies

  • ACGME Review Committee for Surgery
  • American College of Surgeons
  • American Gastroenterological Association
  • American Medical Association
  • American Physiological Society
  • American Society for Clinical Investigation
  • American Surgical Association
  • Americas Hepato-Pancreato-Biliary Association
  • Association for Academic Surgery
  • Association for Surgical Education
  • Central Surgical Association
  • Chicago Surgical Society
  • Cincinnati Surgical Society
  • Gastroenterology Research Group
  • Halsted Society
  • Illinois State Medical Society
  • Illinois Surgical Society
  • International Association of Pancreatology
  • International Society of Surgery
  • International Surgical Group
  • James IV Association of Surgeons
  • Pancreas Club
  • Society for Surgery of the Alimentary Tract
  • Society of Asian Academic Surgeons
  • Society of Black Academic Surgeons
  • Society of Clinical Surgery
  • Society of Surgical Chairs
  • Society of University Surgeons
  • Southern Surgical Association
  • Surgical Biology Club
  • Aetna HMO (specialists only)
  • Aetna POS
  • Aetna PPO
  • BCBS Blue Precision HMO (specialists only)
  • BCBS HMO (HMOI) (specialists only)
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare *see insurance page
  • Aetna Better Health *see insurance page
  • Medicare
  • Multiplan PPO
  • United Choice Plus POS/PPO
  • United Options (PPO)
  • United Select (HMO & EPO) (specialists only)
  • United W500 Emergent Wrap
  • Aetna Medicare Advantage HMO & PPO
  • BCBS Medicare Advantage HMO & PPO
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Choice PFFS
  • Humana Medicare Advantage Gold Plus HMO
  • United Choice HMO (specialists only)
  • University of Chicago Health Plan (UCHP)
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At a Glance

Practicing Since1990

Board Certifications

  • Surgery

Languages Spoken

  • German
  • French
  • English