Gastrointestinal Surgery (GI Surgery), General Surgery, Surgical Oncology | More

Dallas B. Phemister Professor of Surgery Chair, Department of Surgery

A clinically integrated network of physicians and providers employed by UChicago Medicine who offer care in inpatient, community, ambulatory, acute care or extended care settings.

Jeffrey B. Matthews, MD
Jeffrey B. Matthews, MD, is a gastrointestinal surgeon and leading authority on the surgical treatment of diseases of the pancreas, bile ducts, and liver. He is highly skilled in the treatment of acute and chronic pancreatitis, and is one of a handful of surgeons in the nation who has expertise in islet autotransplantation, a treatment that prevents the development of diabetes after surgery for pancreatitis. He also has vast experience in bile duct reconstruction and complex reoperative gastrointestinal surgery.

Dr. Matthews has held several leadership positions during his distinguished career. Currently, he serves as senior director of the American Board of Surgery and president of the Society for Surgery of the Alimentary Tract.

Dr. Matthews' laboratory research explores the fundamental mechanisms used by epithelial tissues to regulate secretion — which goes awry in several diseases, including cystic fibrosis and many types of diarrhea. This research has received long-term support from the National Institutes of Health.

An accomplished author, Dr. Matthews has published over 150 original articles, chapters and editorials. He serves on the editorial board of 11 prestigious surgical and scientific journals and is currently associate editor of the Journal of Gastrointestinal Surgery.

Dr. Matthews is dedicated to teaching and mentoring medical students and new physicians, and has received awards for excellence in teaching. A popular speaker, Dr. Matthews is frequently invited to lecture at universities and medical conferences across the United States and abroad.

Areas of Expertise

Medical Education

  • Harvard Medical School


  • Beth Israel Deaconess Medical Center


  • Beth Israel Deaconess Medical Center


  • University of Bern; Fellowship: Brigham and Women's Hospital

Memberships & Medical Societies

  • The Halsted Society
  • American College of Surgeons
  • American Board of Surgery
  • American Association for the Advancement of Science
  • International Association of Pancreatology
  • Massachusetts Medical Society
  • Society for Surgery of the Alimentary Tract
  • Society for Surgical Chairs
  • Society of Clinical Surgery
  • Society of University Surgeons
  • American Gastroenterological Association
  • American Hepato-Pancreato-Biliary Association
  • Gastroenterology Research Group
  • Association for Surgical Education
  • Association for Academic Surgery
  • American Surgical Association
  • American Society for Clinical Investigation
  • American Society for Bariatric Surgery
  • American Physiological Society
  • American Pancreatic Association
  • American Medical Association
  • Surgical Biology Club
  • Aetna POS
  • Aetna HMO
  • Aetna PPO
  • BCBS Blue Precision HMO
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare
  • Coventry Health Plan PPO
  • Great West PPO
  • Illinicare
  • Medicare
  • Multiplan PPO
  • United Choice / Choice Plus
  • United Options (PPO)
  • United Select (HMO & EPO)
  • United W500 Emergent Wrap
To Request an Appointment

Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

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To Refer a Patient

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At a Glance

Practicing Since1990

Board Certifications

  • Surgery

Languages Spoken

  • German
  • French
  • English