James LaBelle, MD, PhD

Pediatric Hematology & Oncology (Pediatric Cancer) | More

Associate Professor of Pediatrics Director, Hematopoietic Stem Cell Transplantation Program

A clinically integrated network of physicians and providers employed by UChicago Medicine who offer care in inpatient, community, ambulatory, acute care or extended care settings.

James LaBelle, MD, PhD, provides care for children of all ages with cancer and blood diseases, including leukemia and lymphoma. In particular, Dr. LaBelle specializes in stem cell transplantation, replacing a patient's diseased bone marrow and immune system with healthy cells.

Dr. LaBelle's laboratory research focuses on understanding at a molecular level the reason why some pediatric cancers are resistant to therapy. He currently serves as the primary investigator on a study examining a critical network of proteins that regulate whether a malignant cell lives or dies. The normal signaling between these proteins often is disturbed in cancerous cells. Through this research, he hopes to identify novel cell death regulatory mechanisms in resistant hematopoietic malignancies and design effective strategies to overcome them. Dr. LaBelle's research is currently funded by the National Institutes of Health.

A dedicated mentor, Dr. LaBelle also received special recognition for teaching medical students, residents, and fellows about pediatric hematology, oncology and hematopoietic stem cell transplantation.

Medical Education

  • Medical College of Wisconsin


  • Boston Children's Hospital


  • Boston Children's Hospital


  • Dana-Farber Cancer Institute; Children's Hospital Boston

Other Grad Education

  • PhD, University of Wisconsin

Memberships & Medical Societies

  • American Society of Hematology
  • American Association for Cancer Research
  • American Society of Transplantation and Cellular Therapy
  • Aetna POS
  • Aetna HMO
  • Aetna PPO
  • BCBS Blue Precision HMO
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare
  • Coventry Health Plan PPO
  • Great West PPO
  • Illinicare*
  • Medicare
  • Multiplan PPO
  • United Choice / Choice Plus
  • United Options (PPO)
  • United Select (HMO & EPO)
  • United W500 Emergent Wrap
To Request an Appointment

Comer Children's Hospital - Hyde Park

Request an Appointment at Comer Children's Hospital - Hyde Park

To Refer a Patient

Refer a Patient

At a Glance

Practicing Since2006

Board Certifications

  • Pediatrics

Languages Spoken

  • English

At the Forefront Live: Childhood Cancers

UChicago Medicine pediatric oncologists James LaBelle, MD, PhD, and Jennifer McNeer, MD, discuss the advances in cancer treatments and care for teens and young adults with cancer. Plus a special visit from a patient and first baseman Anthony Rizzo.

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