Conditions We Treat with Stem Cell Transplant

Stem cell transplant is being used to treat many types of conditions and can often be used when conventional treatments have been unsuccessful. Stem cell transplantation is an emerging first-line therapy for some serious diseases, including:

• Hematologic malignancies and leukemias particularly:
  • Acute lymphoblastic leukemia (ALL)
  • Acute myelogenous leukemia (AML)
  • Chronic myelogenous leukemia (CML)
  • Juvenile myelomonocytic leukemias (JMML/CMML)
  • Myelodysplastic syndromes (MDS)
  • Secondary leukemias
  • Relapsed/refractory leukemia that has failed other therapies
• Hodgkin and Non-Hodgkin lymphoma
• Neuroblastoma
• Sarcomas
• Other solid tumors of childhood
• Hemophagocytic lymphohistiocytosis (HLH)
• Hemoglobinopathies including sickle cell anemia and β-thalassemia
• Aplastic anemia
• Fanconi anemia
• Rare blood diseases including chronic granulomatous disease, Chediak-Higashi and Schwachman-Diamond syndromes, and dyskeratosis congenital disease
• Paroxysmal nocturnal hemoglobinuria
• Bone marrow failure syndromes
• Metabolic/lysosomal storage diseases
• Immunodeficiencies including severe combined immunodeficiency (SCID) and Wiskott-Aldrich Syndrome
• Autoimmune conditions including systemic lupus erythematosus (SLE), rheumatoid arthritis and scleroderma