No Photo

UChicago Faculty Physicians

Samuel Refetoff, MD

Frederick H. Rawson Professor Emeritus of Medicine Director, Endocrinology Laboratory

Samuel Refetoff, MD, specializes in adult and pediatric endocrinology, with expertise in congenital and inherited thyroid diseases.

His laboratory work focuses on identifying genetic errors that cause defects in thyroid hormone regulation, synthesis, transport and action. Dr. Refetoff has described several genetic diseases of the thyroid, including resistance to thyroid hormone (Refetoff’s syndrome). He has one of the largest referral centers for genetic thyroid disease in the world.

His research work is supported by a MERIT award from the National Institutes of Health, which has resulted in more than 480 publications. He serves on the editorial board of five endocrinology journals.

Areas of Expertise

Memberships & Medical Societies

  • Pediatric Endocrine Society
  • European Thyroid Association
  • American Thyroid Association
  • Canadian Medical Association
  • Association of American Physicians
  • Endocrine Society
  • Royal College of Physicians of Ireland
  • American Society of Human Genetics
  • Bulgarian Academy of Sciences and Arts
  • Belgian Royal Academy of Medicine
  • American Society for Clinical Investigation

Practicing Since

  • 1963

Languages Spoken

  • English
  • Bulgarian
  • Italian
  • French
  • Spanish

Medical Education

  • McGill University


  • Notre Dame University Hospital


  • Good Samaritan Hospital; Lahey Clinic Foundation

News & Research

View Published Papers
  • Aetna HMO (specialists only)
  • Aetna POS
  • Aetna PPO
  • BCBS Blue Precision HMO (specialists only)
  • BCBS HMO (HMOI) (specialists only)
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare *see insurance page
  • Aetna Better Health *see insurance page
  • Medicare
  • Multiplan PPO
  • United Choice Plus POS/PPO
  • United Options (PPO)
  • United Select (HMO & EPO) (specialists only)
  • United W500 Emergent Wrap
  • Aetna Medicare Advantage HMO & PPO
  • BCBS Medicare Advantage HMO & PPO
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Choice PFFS
  • Humana Medicare Advantage Gold Plus HMO
  • United Choice HMO (specialists only)
  • University of Chicago Health Plan (UCHP)

Our list of accepted insurance providers is subject to change at any time. You should contact your insurance company to confirm UChicago Medicine participates in their network before scheduling your appointment. If your insurance company is not listed here, or if you have any other questions, please contact

Why does this provider not have a star rating?

Our goal is to provide our patients and visitors with correct and useful information. We only post provider satisfaction information from clinic surveys when they are returned from patients.

This provider has not had surveys returned that meet the necessary sample size

About Our Star Ratings and Comments:

Randomly selected patients are sent patient satisfaction surveys after their visits. We get thousands of survey responses each year. The responses are used to improve patient experience and recognize staff members for the care they provide. Patient survey responses are also used to make star ratings for each provider.

For the star ratings and comments, all feedback on the provider web page is posted as it was given from patients. Comments that do not apply, risk patient privacy, or are not appropriate are not posted. Star ratings and comments come from a number of survey questions. A star rating is not given if a provider only has a small number of survey responses.

Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

Request an Appointment at Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

To Refer a Patient

Refer a Patient