Fighting Cancer by Turning On the Immune System
There’s a breakthrough in the fight against cancer, and it’s making headlines around the world. Called CAR T-cell therapy, the treatment supercharges a patient’s white blood cells to seek out and destroy cancer cells. Research at the David and Etta Jonas Center for Cellular Therapy at UChicago Medicine played a key role in the development of this exciting new immunotherapy for certain cancers.
Select medical centers in the United States, including UChicago Medicine, led clinical trials of this new treatment for leukemia and lymphoma. After promising results in adults and children, the FDA has approved CAR T-cell therapy for the treatment of specific types of these blood cancers. UChicago Medicine was the first site in the country to be certified for FDA-approved CAR T-cell therapies for specific blood cancers in both adult and pediatric patients. Our specialists are conducting clinical trials of CAR T-cell therapy and other cellular therapies for other forms of blood cancers as well as for solid tumors such as cervical cancer and non-small cell lung cancer.
What Is CAR T-cell Therapy?
CAR (Chimeric Antigen Receptor) T-cell therapy is an emerging form of cancer immunotherapy, which involves supercharging a patient’s T cells to recognize and attack cancer cells. CAR T-cell therapy is a type of cellular therapy.
During clinical trials of CAR T-cell therapy, 70 to 90 percent of patients with acute lymphoblastic (lymphocytic) leukemia (ALL) went into remission after this treatment. And 40 to 50 percent of patients with non-Hodgkin lymphoma experienced complete remission. While it’s too early to say these patients are cured, the results are encouraging for individuals with hard-to-treat (refractory) or relapsed leukemia or lymphoma. Learn more about how CAR T-cell therapy works.
Learn about the CAR T-cell therapy multi-step process, view a video and download an infographic about the procedure.
CAR T-cell Therapy Patient Stories & News
Clinical Trials of New Cellular Therapies
Our physicians work to bring the latest breakthroughs in cellular therapy treatments quickly to their patients’ bedsides. Several new cellular therapies are now being tested through clinical trials for blood cancers and solid tumors.
Convenient Locations for Cancer Care
Request an Appointment for CAR T-Cell Therapy
You can also make an appointment with our providers by:
– Scheduling a virtual video visit to see a provider from the comfort of your home
– Requesting an online second opinion from our specialists
– Filling out an online questionnaire (e-visit) to get a same-day diagnosis and treatment for common conditions.
To speak to someone directly, please call 1-844-482-7823. If you have symptoms of an urgent nature, please call your doctor or go to the emergency room immediately.
Online Second Opinions
Rather than coming to a UChicago Medicine location for a second opinion, you can receive a remote second opinion from our cancer specialists without having to leave home. Remote second opinions are available for both adult and pediatric patients from any location in the world.
For Referring Physicians
To refer a patient for CAR T-cell therapy, please call 1-844-482-7832.
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