Marcus R. Clark, MD

Rheumatology | More

Professor of Medicine and Pathology Chief, Section of Rheumatology
Co-Director, Knapp Center for Lupus and Immunology Research

A clinically integrated network of physicians and providers employed by UChicago Medicine who offer care in inpatient, community, ambulatory, acute care or extended care settings.

Marcus R. Clark, MD, is a nationally known expert in arthritis and autoimmune disease, including rheumatoid and psoriatic arthritis, lupus, scleroderma and osteoarthritis.

Funded by the National Institutes of Health, Dr. Clark’s research examines the key cellular components of the immune process with the goal of understanding the mechanisms and changing the course of autoimmune disease. He is also exploring the role that immune cells play in contributing to the kidney damage sometimes seen in lupus patients.

Dr. Clark is the author of more than 70 peer-reviewed articles in prestigious scientific journals including Science, Nature Immunology, Proceedings of the National Academy of Sciences and the Public Library of Science’s (PLoS) Biology and Immunity.


Areas of Expertise

  • Lupus
  • Psoriatic Arthritis
  • Rheumatoid Arthritis

Medical Education

  • University of California Irvine School of Medicine


  • Michigan Medicine


  • Michigan Medicine


  • University of California San Francisco Health

Memberships & Medical Societies

  • American Association of Immunologists
  • American College of Rheumatology
  • American Society for Clinical Investigation
  • Henry Kunkel Society
  • Aetna POS
  • Aetna HMO
  • Aetna PPO
  • BCBS Blue Precision HMO
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare
  • Coventry Health Plan PPO
  • Great West PPO
  • Illinicare*
  • Medicare
  • Multiplan PPO
  • United Choice / Choice Plus
  • United Options (PPO)
  • United Select (HMO & EPO)
  • United W500 Emergent Wrap
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At a Glance

Practicing Since1984

Board Certifications

  • Internal Medicine
  • Rheumatology

Languages Spoken

  • English