Marcus R. Clark, MD

Rheumatology | More

Professor of Medicine and Pathology Chief, Section of Rheumatology
Co-Director, Knapp Center for Lupus and Immunology Research

UChicago Faculty Physicians hold faculty positions with the University of Chicago and provide care for patients on the academic health system’s main campus in Hyde Park and in care centers throughout the Chicago region.

Marcus R. Clark, MD, is a nationally known expert in arthritis and autoimmune disease, including rheumatoid and psoriatic arthritis, lupus, scleroderma and osteoarthritis.

Funded by the National Institutes of Health, Dr. Clark’s research examines the key cellular components of the immune process with the goal of understanding the mechanisms and changing the course of autoimmune disease. He is also exploring the role that immune cells play in contributing to the kidney damage sometimes seen in lupus patients.

Dr. Clark is the author of more than 70 peer-reviewed articles in prestigious scientific journals including Science, Nature Immunology, Proceedings of the National Academy of Sciences and the Public Library of Science’s (PLoS) Biology and Immunity.


Areas of Expertise

  • Lupus
  • Psoriatic Arthritis
  • Rheumatoid Arthritis

Medical Education

  • University of California Irvine School of Medicine


  • Michigan Medicine


  • Michigan Medicine


  • University of California San Francisco Health

Memberships & Medical Societies

  • American Association of Immunologists
  • American College of Rheumatology
  • American Society for Clinical Investigation
  • Henry Kunkel Society
  • Aetna HMO (specialists only)
  • Aetna POS
  • Aetna PPO
  • BCBS Blue Precision HMO (specialists only)
  • BCBS HMO (HMOI) (specialists only)
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare *see insurance page
  • Aetna Better Health *see insurance page
  • Medicare
  • Multiplan PPO
  • United Choice Plus POS/PPO
  • United Options (PPO)
  • United Select (HMO & EPO) (specialists only)
  • United W500 Emergent Wrap
  • Aetna Medicare Advantage HMO & PPO
  • BCBS Medicare Advantage HMO & PPO
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Choice PFFS
  • Humana Medicare Advantage Gold Plus HMO
  • United Choice HMO (specialists only)
  • University of Chicago Health Plan (UCHP)
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At a Glance

Practicing Since1984

Board Certifications

  • Internal Medicine
  • Rheumatology

Languages Spoken

  • English