Physician-scientists at University of Chicago Medicine Comer Children's conduct groundbreaking research and clinical trials for a wide range of gastroenterology conditions. Our team is actively involved in basic, clinical and translational research projects that help advance treatment options and improve quality of life for children with these conditions.

  • Examining the quality of life for pediatric patients with celiac disease
  • Optimizing behavioral health among adolescents with celiac disease
  • Evaluating the accuracy of blood testing for patients on a gluten-free diet
  • Offering registry for celiac disease

Evaluating treatment outcomes of Fidaxomicin vs. Vancomycin in recurrent pediatric C. difficile infection

  • Analyzing esophageal microbiome in children with eosinophilic esophagitis and the potential changes with diet
  • Providing registry for gastroenterology eosinophilic esophagitis
  • Examining the effect and success rates of fecal microbial transplantation for Clostridium difficile infection in children
  • Providing registry for fecal microbiota transplant
  • Studying the changes in prevalence of IBD over time among family members of pediatric IBD patients
  • Exploring the risk stratification and identification of immunogenetic and microbial markers of rapid disease progression in children with Crohn’s disease
  • Examining sexual differences in statural growth impairment in pediatric Crohn's disease
  • Analyzing sexual differences in growth impairment in pediatric Crohn's disease
  • Evaluating the use of Humira (Adalimumab) in moderate to severe ulcerative colitis in children
  • Studying growth after the initial menstrual cycle in pediatric female patients with IBD

Registry for liver transplantation (SPLIT)

  • Examining the use and outcomes of Pediatric Parenteral Nutrition Support Therapy
  • Assessing safe and effective doses of Kabiven
  • Offering registry for nutrition care
Postdoctoral researcher Romain Bouziat from the Department of Medicine at the University of Chicago Celiac Disease Center

Active Clinical Trials

We are dedicated to delivering new treatments through our research and clinical trials. Offering patients advanced therapies before they are widely available puts them at the forefront of gastroenterology care.

Learn About Pediatric GI Clinical Trials