Cancer cells cooperate to fight off the immune system and overcome therapy

New research from the lab of Thomas Gajewski, MD, PhD, showed that tumor cells can escape T cell killing during immunotherapy by using “clonal cooperation.” This work suggests that early treatment with immunotherapies may be more effective, before tumor cell heterogeneity emerges.

After years of treatment and three relapses, CAR T-cell therapy offers hope for leukemia patient
CAR T-cell update: therapy improves outcomes for patients with B-cell lymphoma