Cancer cells cooperate to fight off the immune system and overcome therapy
New research from the lab of Thomas Gajewski, MD, PhD, showed that tumor cells can escape T cell killing during immunotherapy by using “clonal cooperation.” This work suggests that early treatment with immunotherapies may be more effective, before tumor cell heterogeneity emerges.
After years of treatment and three relapses, CAR T-cell therapy offers hope for leukemia patient
Jacelyn Walsh, a 41-year-old mother of two, relapsed three times in her battle with acute lymphoblastic leukemia. After trying CAR T-cell therapy at UChicago Medicine, she has hope for the future.
CAR T-cell update: therapy improves outcomes for patients with B-cell lymphoma
An international phase-2 trial of a CAR T-cell therapy found that 52 percent of patients responded favorably.
