Daniel H. Gruenstein, MD

Pediatric Cardiology | More

Associate Professor of Pediatrics Director, Pediatric Catheterization Lab
Co-Director, Chicago Pediatric Heart Center

UChicago Faculty Physicians hold faculty positions with the University of Chicago and provide care for patients on the academic health system’s main campus in Hyde Park and in care centers throughout the Chicago region.

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Daniel H. Gruenstein, MD, cares for infants, children, teens and adults with congenital heart disease – abnormalities that affect the structure and function of a patient's heart. He specializes in interventional cardiology, including intravascular stent placement, valve implantation and hybrid cardiac catheterization procedures.

Dr. Gruenstein's research focuses on innovations in cardiac device development. He serves as the primary investigator on several studies that test new devices in preclinical and FDA approved settings. In addition, Dr. Gruenstein was one of 7 clinicians nationwide invited by the Society for Cardiovascular Angiography & Intervention to participate in the design and creation of a biodegradable stent for pediatric patients. He holds several provisional patents for his work.

A devoted educator, Dr. Gruenstein mentors medical students, residents and fellows in interventional cardiology. As one of only five instructors, Dr. Gruenstein trains approximately 20 percent of all cardiologists in the United States who use the Amplatzer Atrial Septal Occluder Device to treat atrial septal defects (holes in the wall between the upper chambers of the heart). He has directed several national hands-on workshops for adult and pediatric interventional cardiologists, teaching advanced therapeutic techniques.

Dr. Gruenstein has made significant contribution to the medical literature, publishing abstracts, peer-reviewed articles, book chapters and more on key topics in pediatric cardiology. In addition, he was a founding member and the inaugural president of the Pediatric/Congenital Interventional Cardiology Early-career Society (PICES), an international organization that promotes early faculty development and performs multi-center studies.

The recipient of numerous national awards, Dr. Gruenstein has been recognized by patients, students and peers alike. He has been honored with the Patients' Choice Award and Compassionate Doctor Award, and has been named to the list of Best Doctors in America by Best Doctors, Inc.


Areas of Expertise

Medical Education

  • University of Cincinnati College of Medicine


  • Cincinnati Children's Hospital


  • Cincinnati Children's Hospital Medical Center


  • Cincinnati Children's Hospital Medical Center

Memberships & Medical Societies

  • Society for Cardiovascular Angiography and Interventions
  • Aetna HMO (specialists only)
  • Aetna POS
  • Aetna PPO
  • BCBS Blue Precision HMO (specialists only)
  • BCBS HMO (HMOI) (specialists only)
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare *see insurance page
  • Aetna Better Health *see insurance page
  • Medicare
  • Multiplan PPO
  • United Choice Plus POS/PPO
  • United Options (PPO)
  • United Select (HMO & EPO) (specialists only)
  • United W500 Emergent Wrap
  • Aetna Medicare Advantage HMO & PPO
  • BCBS Medicare Advantage HMO & PPO
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Choice PFFS
  • Humana Medicare Advantage Gold Plus HMO
  • United Choice HMO (specialists only)
  • University of Chicago Health Plan (UCHP)
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At a Glance

Practicing Since1999

Board Certifications

  • Adult Congenital Heart Disease
  • Pediatrics
  • Pediatric Cardiology

Languages Spoken

  • English