Babak Mokhlesi, MD, MSc

Pulmonary Medicine (Pulmonology), Critical Care Medicine, Sleep Medicine | More

Professor of Medicine Director, Sleep Disorders Center
Director, Sleep Medicine Fellowship Program

UChicago Faculty Physicians hold faculty positions with the University of Chicago and provide care for patients on the academic health system’s main campus in Hyde Park and in care centers throughout the Chicago region.

Babak Mokhlesi, MD, MSc, is a pulmonologist and an expert in sleep disorders. He treats patients with a wide variety of sleep disorders, ranging from respiratory disorders of sleep -- such as sleep apnea and obesity hypoventilation syndrome -- to non-respiratory sleep disorders including narcolepsy, restless legs syndrome, parasomnias, circadian rhythm disorders and insomnia. In his practice, Dr. Mokhlesi cares for patients in clinic as well as in the intensive care unit.

During the last few years, his research has focused on obstructive sleep apnea, with a specific focus on REM-related sleep-disordered breathing, perioperative complications in patients with sleep apnea, as well as best treatment strategies in patients with obesity hypoventilation syndrome. He is also interested in studying the impact of continuous positive airway pressure (CPAP) therapy on metabolic and cardiovascular outcomes in obstructive sleep apnea.

In addition to authoring several book chapters and articles, Dr. Mokhlesi is an associate editor for journal Thorax and the Journal of Clinical Sleep Medicine. He also serves on the editorial board of Chest.

Areas of Expertise

Medical Education

  • University of Monterrey


  • Weiss Memorial Hospital


  • Weiss Memorial Hospital


  • Northwestern Medicine

Memberships & Medical Societies

  • American College of Chest Physicians
  • American Academy of Sleep Medicine
  • American Thoracic Society
  • Society of Thoracic Surgeons
  • Aetna HMO (specialists only)
  • Aetna POS
  • Aetna PPO
  • BCBS Blue Precision HMO (specialists only)
  • BCBS HMO (HMOI) (specialists only)
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare *see insurance page
  • Aetna Better Health *see insurance page
  • Medicare
  • Multiplan PPO
  • United Choice Plus POS/PPO
  • United Options (PPO)
  • United Select (HMO & EPO) (specialists only)
  • United W500 Emergent Wrap
  • Aetna Medicare Advantage HMO & PPO
  • BCBS Medicare Advantage HMO & PPO
  • Humana Medicare Advantage Choice PPO
  • Humana Medicare Advantage Gold Choice PFFS
  • Humana Medicare Advantage Gold Plus HMO
  • United Choice HMO (specialists only)
  • University of Chicago Health Plan (UCHP)
To Request an Appointment

Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

Request an Appointment at Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

UChicago Medicine River East

Request an Appointment at UChicago Medicine River East

To Refer a Patient

Refer a Patient

At a Glance

Practicing Since2000

Board Certifications

  • Pulmonary Medicine
  • Internal Medicine
  • Critical Care Medicine
  • Sleep Medicine

Languages Spoken

  • Farsi
  • Spanish
  • English

At The Forefront Live: Understanding Sleep Apnea

UChicago Medicine experts Babak Mokhlesi, MD, director of the University of Chicago Medicine’s Sleep Disorder Center and colleagues Zhen Gooi, MD and Hemal Nayak, MD discuss sleep apnea, and the multidisciplinary approach to treatment.

Babak Mokhlesi, MD, Zhen Gooi, MD and Hemal Nayak, MD discuss sleep apnea treatments
Watch Video