Babak Mokhlesi, MD, MSc

Pulmonary Medicine (Pulmonology), Critical Care Medicine, Sleep Medicine | More

Professor of Medicine Director, Sleep Disorders Center
Director, Sleep Medicine Fellowship Program

A clinically integrated network of physicians and providers employed by UChicago Medicine who offer care in inpatient, community, ambulatory, acute care or extended care settings.

Babak Mokhlesi, MD, MSc, is a pulmonologist and an expert in sleep disorders. He treats patients with a wide variety of sleep disorders, ranging from respiratory disorders of sleep -- such as sleep apnea and obesity hypoventilation syndrome -- to non-respiratory sleep disorders including narcolepsy, restless legs syndrome, parasomnias, circadian rhythm disorders and insomnia. In his practice, Dr. Mokhlesi cares for patients in clinic as well as in the intensive care unit.

During the last few years, his research has focused on obstructive sleep apnea, with a specific focus on REM-related sleep-disordered breathing, perioperative complications in patients with sleep apnea, as well as best treatment strategies in patients with obesity hypoventilation syndrome. He is also interested in studying the impact of continuous positive airway pressure (CPAP) therapy on metabolic and cardiovascular outcomes in obstructive sleep apnea.

In addition to authoring several book chapters and articles, Dr. Mokhlesi is an associate editor for journal Thorax and the Journal of Clinical Sleep Medicine. He also serves on the editorial board of Chest.

Areas of Expertise

Medical Education

  • University of Monterrey


  • Weiss Memorial Hospital


  • Weiss Memorial Hospital


  • Northwestern Medicine

Memberships & Medical Societies

  • American College of Chest Physicians
  • American Academy of Sleep Medicine
  • American Thoracic Society
  • Society of Thoracic Surgeons
  • Aetna POS
  • Aetna HMO
  • Aetna PPO
  • BCBS Blue Precision HMO
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • CountyCare
  • Coventry Health Plan PPO
  • Great West PPO
  • Illinicare*
  • Medicare
  • Multiplan PPO
  • United Choice / Choice Plus
  • United Options (PPO)
  • United Select (HMO & EPO)
  • United W500 Emergent Wrap
To Request an Appointment

Duchossois Center for Advanced Medicine (DCAM) - Hyde Park

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UChicago Medicine River East

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To Refer a Patient

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At a Glance

Practicing Since2000

Board Certifications

  • Pulmonary Medicine
  • Internal Medicine
  • Critical Care Medicine
  • Sleep Medicine

Languages Spoken

  • Farsi
  • Spanish
  • English

At The Forefront Live: Understanding Sleep Apnea

UChicago Medicine experts Babak Mokhlesi, MD, director of the University of Chicago Medicine’s Sleep Disorder Center and colleagues Zhen Gooi, MD and Hemal Nayak, MD discuss sleep apnea, and the multidisciplinary approach to treatment.

Watch Video