CLINICAL TRIAL / NCT06191198

Communication Bridge 3 Study

Interventional
Recruiting
NCT06191198

Eligibility Details Visit Clinicaltrials.gov

Contact Information

Daniel Persky

Communication Bridge: Optimizing an Evidence-based Intervention for Individuals With Primary Progressive Aphasia

This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study is to help us better understand the effects of speech-language therapy on communication abilities in individuals with PPA.

Detailed Description

Participants with a diagnosis of PPA and their actively-engaged care partners will be involved in the study for approximately 17 months. Each participant will receive a laptop equipped with the necessary applications and features for the study. Participants will receive up to 10 evaluations and 20 speech therapy sessions with a licensed speech therapist, as well as access to Communication Bridge, a personalized web application to practice home exercises that reinforce treatment strategies. There are no costs to participate in this study.

Eligibility Details

Gender
All

Age Group
18 Years to 100 Years

Accepting Healthy Volunteers
No

Inclusion Criteria (person with PPA): 1. Meets diagnostic criteria for PPA based on neurologist and supporting medical assessments (extracted from medical records) 2. English as primary language used in daily communication activities (by self-report) 3. Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report) 4. Adequate vision (aided or unaided) for reading a newspaper, or other functional materials (by self-report) 5. Able to pass technology screening and demonstrates sufficient knowledge for use of video conference and Communication Bridgeâ„¢ web application use (with or without training) 6. Geriatric Depression Scale score â‰¤ 9 7. Mild-moderate PPA informed by a structured interview with a speech-language pathologist and a standardized testing battery. Inclusion Criteria (Co-enrolled communication partner): 1. 18+ years of age 2. English as primary language used in daily communication activities (by self-report) 3. Adequate hearing (aided or unaided) for communicating with others in a crowded room (by self-report) 4. Able to pass technology screening* and demonstrates sufficient knowledge for use of video conference and Communication Bridgeâ„¢ web application use (with or without training) Exclusion Criteria: - A dementia diagnosis other than Primary Progressive Aphasia - Participation is co-enrolled in an outside speech language therapy program during the study course. - Communication partners will be excluded if they have a pre-existing communication impairment that would affect study participation (e.g., aphasia, dementia) Medical records will be requested and reviewed to determine eligibility