UChicago Medicine Comer Children's

PHACE Syndrome

What is PHACE Syndrome? 

PHACE (posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, eye abnormalities, sternal cleft and supraumbilical raphe) syndrome is a rare condition that includes a constellation of these congenital anomalies. Individuals with PHACE always have at least one facial hemangioma but may also experience two or three of the other associated abnormalities. The hemangioma is generally a flattened and thickened area of tissue.

Diagnosis & Treatment

The diagnosis and treatment of PHACE syndrome often requires several types of pediatric experts. The vascular anomalies team at Comer Children's evaluates, treats and monitors the vascular malformations associated with the syndrome and works closely with other specialists involved in the patient's care.

Treatments for vascular malformations related to PHACE syndrome may include:

  • Surgical removal (excision) of the malformation
  • Laser therapy to shrink the affected blood vessels
  • Sclerotherapy: Injection of a solution directly in the vein, causing it to collapse and forcing the blood to reroute through healthier veins
  • Medical treatment for hemangiomas

Why Choose Us?

The vascular anomalies program at Comer Children's offers an integrated and comprehensive approach to the diagnosis, care and management of vascular malformations. Our multidisciplinary team of pediatric experts works together to educate families and to evaluate and treat children with all types of these vascular lesions.

Resources & Support for Patients with Vascular Anomalies

Patient Resources at Comer Children’s

Kids want to feel like kids, even when they're sick. Our Child Life therapists use play, art and other approaches to take some of the scare away from the hospital experience and to help kids feel as normal as possible, in spite of their disease. Located near Comer Children's, the Ronald McDonald House provides a home away from home for families while their child is hospitalized.

Patient Resources & Support Groups

These organizations and support groups may be helpful to families and patients by providing support, education and treatment information on vascular anomalies.