Circadian Function and Cardio-metabolic Risk in Adrenal Insufficiency: a Case Control Study
The purpose of this study is to compare cardio-metabolic risk, glucose tolerance, and night time blood pressure between healthy control subjects and patients with adrenal insufficiency. No intervention will be administered and the study is observational only.
A secondary hypothesis of the study is that adrenal insufficiency patients on a replacement regimen (as part of their standard of care ongoing treatment) that results in daytime cortisol profiles approximating the normal diurnal variation will have better cardio-metabolic function than adrenal insufficiency patients who have grossly abnormal cortisol profiles.
18 Years and up
Accepting Healthy Volunteers?
Accepts Healthy Volunteers
- Primary or secondary adrenal insufficiency, Healthy matched controls, acute or unstable health conditions age 18 or older
- Diabetes, Tertiary adrenal insufficiency