18 Years to 99 Years
Accepting Healthy Volunteers?
Adult male or female subjects with pathologically confirmed MDS who failed to respond,
relapsed after an initial response, or were unable to tolerate hypomethylating agents, ECOG
performance status of 0 - 2, and adequate organ and marrow function.
Concurrent chemotherapy, immunotherapy, biologic, or hormonal therapy for cancer treatment,
prior MAb against CTLA-4, PD-1, or PD-L1, alllogenic or haploidentical transplant, current
immunosuppressive medication or autoimmune or inflammatory disease.