Gender
All
Age Group
21 Years to 70 Years
Accepting Healthy Volunteers
No
Inclusion Criteria:
- Symptomatic multiple myeloma of any subtype in any disease stage, providing that
patient does not have smoldering myeloma.
- Patient must otherwise be a candidate for ASCT as determined by treating physician.
- No current CNS Myeloma at time of enrollment.
- Life expectancy greater than 12 weeks.
- Age greater than or equal to 21 and less than or equal to 70 years old.
- EGOG performance status less than or equal to 2.
- No cardiac, pulmonary, hepatic, or renal contraindications for high dose chemotherapy.
- HIV Negative.
- No active Hepatitis B or C.
- Patients must be able to provide written informed, consent.
Exclusion Criteria:
- Pregnant or nursing women. Women of child-bearing age must be tested for pregnancy.
- Use of systemic immunosuppressive medications, including corticosteroids, tacrolimus,
mycophenolate mofetil, sirolimus or cyclosporine A.
- Psychiatric illness which may make compliance to the clinical protocol unmanageable or
which may compromise the ability of the patient to give informed consent.
- Active autoimmune disease including but not limited to: rheumatoid arthritis
inflammatory bowel disease, celiac disease, systemic lupus erythematosis, scleroderma
or multiple sclerosis.
