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Most cases of ovarian cancer are found at an advanced stage because there are few early symptoms. Due to the complex biology of the disease, the development of effective medications has been particularly challenging for scientists. For these reasons, the ovarian cancer team at the University of Chicago Medicine integrates medical care with ongoing clinical, basic and translational research. Our comprehensive care offers patients the most advanced treatments and technologies while asking questions that may lead to the next novel therapies. Our goal is to better understand the disease while providing optimum care for our patients.
Our ovarian cancer physician-scientists are members of the internationally recognized UChicago Medicine Comprehensive Cancer Center (UCCCC), an NCI-designated cancer research center. As part of this consortium of select cancer research centers, our program — and our patients — have access to emerging therapies and the highest level of care for ovarian cancer. This includes Phase 1 clinical trials, the earliest study of new medications or protocols typically available in just a few centers. Gynecologic oncologist John Moroney, MD, and medical oncologist Gini Fleming, MD, work together to find the best clinical trials for patients, and share these recommendations with our multidisciplinary tumor board that meets each week. Find an ovarian cancer clinical trial.
UChicago Medicine is home to a large ovarian cancer research laboratory led by Ernst Lengyel, MD, PhD. It is dedicated to improving the understanding of the biology of ovarian cancer metastasis and to exploring new drugs for its treatment. The scientific work is integrated into the clinical care we offer to women with this disease. In recent years, researchers in the lab published findings in leading scientific journals, characterized two new targets in ovarian cancer that led to clinical trials, and developed a novel method to find new drugs.
Ovarian cancer research at UChicago Medicine focuses on: